Phenotype molding of stromal cells in the lung tumor microenvironment
Phenotype molding of stromal cells in the lung tumor microenvironment
About this item
Full title
Author / Creator
Lambrechts, Diether , Wauters, Els , Boeckx, Bram , Aibar, Sara , Nittner, David , Burton, Oliver , Bassez, Ayse , Decaluwé, Herbert , Pircher, Andreas , Van den Eynde, Kathleen , Weynand, Birgit , Verbeken, Erik , De Leyn, Paul , Liston, Adrian , Vansteenkiste, Johan , Carmeliet, Peter , Aerts, Stein and Thienpont, Bernard
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cancer cells are embedded in the tumor microenvironment (TME), a complex ecosystem of stromal cells. Here, we present a 52,698-cell catalog of the TME transcriptome in human lung tumors at single-cell resolution, validated in independent samples where 40,250 additional cells were sequenced. By comparing with matching non-malignant lung samples, we...
Alternative Titles
Full title
Phenotype molding of stromal cells in the lung tumor microenvironment
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2067882489
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2067882489
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0096-5
