Log in to save to my catalogue

Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its ac...

Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its ac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2075546127

Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its active metabolites

About this item

Full title

Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its active metabolites

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

European journal of clinical pharmacology, 2018-11, Vol.74 (11), p.1417-1426

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
CYP3A4, CYP2C19, and CYP3A5 are primarily involved in the metabolism of cilostazol. We investigated the effects of
CYP2C19
and
CYP3A5
genetic polymorphisms on the pharmacokinetics of cilostazol and its two active metabolites.
Methods
Thirty-three healthy Korean volunteers were administered a single 100-mg oral dose of c...

Alternative Titles

Full title

Effects of CYP2C19 and CYP3A5 genetic polymorphisms on the pharmacokinetics of cilostazol and its active metabolites

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2075546127

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2075546127

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-018-2522-5

How to access this item