Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4 super(+) T cells
Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4 super(+) T cells
About this item
Full title
Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4 super(+) T cells
Author / Creator
Journal title
Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (29), p.10107-10112
Language
English
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Scope and Contents
Contents
TNF-a plays an important role in immune regulation, inflammation, and autoimmunity. Chronic TNF exposure has been shown to down-modulate T cell responses. In a mouse T cell hybridoma model, TNF attenuated T cell receptor (TCR) signaling. We have confirmed that chronic TNF and anti-TNF exposure suppressed and increased T cell responses, respectively...
Alternative Titles
Full title
Genomic expression profiling of TNF-a-treated BDC2.5 diabetogenic CD4 super(+) T cells
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_20894265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_20894265
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
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