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The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2095528215

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

About this item

Full title

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-09, Vol.561 (7721), p.132-136

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The human genome contains thousands of long non-coding RNAs
1
, but specific biological functions and biochemical mechanisms have been discovered for only about a dozen
2

7
. A specific long non-coding RNA—non-coding RNA activated by DNA damage (
NORAD
)—has recently been shown to be required for maintaining genomic stabil...

Alternative Titles

Full title

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2095528215

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2095528215

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0453-z

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