The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The human genome contains thousands of long non-coding RNAs
1
, but specific biological functions and biochemical mechanisms have been discovered for only about a dozen
2
–
7
. A specific long non-coding RNA—non-coding RNA activated by DNA damage (
NORAD
)—has recently been shown to be required for maintaining genomic stabil...
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Full title
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
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TN_cdi_proquest_miscellaneous_2095528215
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2095528215
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0453-z