The acute blood pressure‐lowering effect of amiloride is independent of endothelial ENaC and eNOS in...
The acute blood pressure‐lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice
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Publisher
England: Wiley Subscription Services, Inc
Journal title
Language
English
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Publisher
England: Wiley Subscription Services, Inc
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Scope and Contents
Contents
Aims
The epithelial sodium channel (ENaC) is expressed in cultured endothelial cells and inhibitory coupling to eNOS activity has been proposed. The present study tested the hypothesis that ENaC blockers increase systemic NO‐products and lower blood pressure in patients and mice, depending on eNOS.
Methods
NO‐products and cGMP were measure...
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Full title
The acute blood pressure‐lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice
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TN_cdi_proquest_miscellaneous_2111153418
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2111153418
Other Identifiers
ISSN
1748-1708
E-ISSN
1748-1716
DOI
10.1111/apha.13189
