Can GABA turn pancreatic α-cells into β-cells?
Can GABA turn pancreatic α-cells into β-cells?
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The neurotransmitter GABA has been shown to induce the transdifferentiation of α-cells into β-cells, restoring normoglycaemia in a mouse model of diabetes mellitus. A recent paper by Amanda Ackermann and colleagues, however, failed to reproduce these findings. Here, we discuss the discrepant findings and propose a systematic approach to solve the c...
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Full title
Can GABA turn pancreatic α-cells into β-cells?
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TN_cdi_proquest_miscellaneous_2112612750
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2112612750
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ISSN
1759-5029
E-ISSN
1759-5037
DOI
10.1038/s41574-018-0101-6
