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Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges
Author / Creator:Brahma, Manoja K. ; Gilglioni, Eduardo H. ; Zhou, Lang ; Trépo, Eric ; Chen, Pengyu ; Gurzov, Esteban N.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-08, Vol.40 (33), p.5155-5167
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Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation
Author / Creator:Bell, Kirstine J ; Saad, Sonia ; Tillett, Bree J ; McGuire, Helen M ; Bordbar, Sara ; Yap, Yu Anne ; Nguyen, Long T ; Wilkins, Marc R ; Corley, Susan ; Brodie, Shannon ; Duong, Sussan ; Wright, Courtney J ; Twigg, Stephen ; de St Groth, Barbara Fazekas ; Harrison, Leonard C ; Mackay, Charles R ; Gurzov, Esteban N ; Hamilton-Williams, Emma E ; Mariño, Eliana
Publisher:England: BioMed Central
Journal title:Microbiome, 2022-01, Vol.10 (1), p.9-9, Article 9
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Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB
Author / Creator:CUNHA, Daniel A ; LADRIERE, Laurence ; ORTIS, Fernanda ; IGOILLO-ESTEVE, Mariana ; GURZOV, Esteban N ; LUPI, Roberto ; MARCHETTI, Piero ; EIZIRIK, Décio L ; CNOP, Miriam
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-12, Vol.58 (12), p.2851-2862
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SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome
Author / Creator:Tillett, Bree J. ; Dwiyanto, Jacky ; Secombe, Kate R. ; George, Thomas ; Zhang, Vivian ; Anderson, Dovile ; Duggan, Emily ; Giri, Rabina ; Loo, Dorothy ; Stoll, Thomas ; Morrison, Mark ; Begun, Jakob ; Hill, Michelle M. ; Gurzov, Esteban N. ; Bell, Kirstine J. ; Saad, Sonia ; Barlow, Christopher K. ; Creek, Darren J. ; Chong, Chun Wie ; Mariño, Eliana ; Hamilton-Williams, Emma E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2893-20, Article 2893
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Inhibition of Y1 receptor signaling improves islet transplant outcome
Author / Creator:Loh, Kim ; Shi, Yan-Chuan ; Walters, Stacey ; Bensellam, Mohammed ; Lee, Kailun ; Dezaki, Katsuya ; Nakata, Masanori ; Ip, Chi Kin ; Chan, Jeng Yie ; Gurzov, Esteban N. ; Thomas, Helen E. ; Waibel, Michaela ; Cantley, James ; Kay, Thomas W. ; Yada, Toshihiko ; Laybutt, D. Ross ; Grey, Shane T. ; Herzog, Herbert
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-09, Vol.8 (1), p.490-12, Article 490
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The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells
Author / Creator:Moore, Fabrice ; Santin, Izortze ; Nogueira, Tatiane C ; Gurzov, Esteban N ; Marselli, Lorella ; Marchetti, Piero ; Eizirik, Decio L
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e31062-e31062
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Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance
Author / Creator:Colli, Maikel L ; Nogueira, Tatiane C ; Allagnat, Florent ; Cunha, Daniel A ; Gurzov, Esteban N ; Cardozo, Alessandra K ; Roivainen, Merja ; Op de Beeck, Anne ; Eizirik, Decio L
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2011-09, Vol.7 (9), p.e1002267-e1002267
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Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets
Author / Creator:Wali, Jibran A ; Gurzov, Esteban N ; Fynch, Stacey ; Elkerbout, Lorraine ; Kay, Thomas W ; Masters, Seth L ; Thomas, Helen E
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-11, Vol.9 (11), p.e113128-e113128
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JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
Author / Creator:Gurzov, Esteban N ; Ortis, Fernanda ; Bakiri, Latifa ; Wagner, Erwin F ; Eizirik, Decio L
Publisher:United States: Public Library of Science
Journal title:PloS one, 2008-08, Vol.3 (8), p.e3030
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Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System
Author / Creator:Gurzov, Esteban N. ; Thomas, Helen E. ; Varanasi, L. Chitra ; Stanley, William J. ; Saadi, Hamdi ; Pappas, Evan G. ; Wali, Jibran A. ; Litwak, Sara A. ; Kay, Thomas W. H.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of diabetes research, 2015-01, Vol.2015 (2015), p.1-16
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PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim
Author / Creator:SANTIN, Izortze ; MOORE, Fabrice ; COLLI, Maikel L ; GURZOV, Esteban N ; MARSELLI, Lorella ; MARCHETTI, Piero ; EIZIRIK, Decio L
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-12, Vol.60 (12), p.3279-3288
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Can GABA turn pancreatic α-cells into β-cells?
Author / Creator:Eizirik, Decio L. ; Gurzov, Esteban N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Endocrinology, 2018-11, Vol.14 (11), p.629-630
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Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death
Author / Creator:ARIF, Sefina ; MOORE, Fabrice ; GUO CAI HUANG ; GURZOV, Esteban N ; PUJOL-BORRELL, Ricardo ; EIZIRIK, Decio L ; PEAKMAN, Mark ; MARKS, Katherine ; BOUCKENOOGHE, Thomas ; DAYAN, Colin M ; PLANAS, Raquel ; VIVES-PI, Marta ; POWRIE, Jake ; TREE, Timothy ; MARCHETTI, Piero
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-08, Vol.60 (8), p.2112-2119
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Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress―Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis
Author / Creator:CUNHA, Daniel A ; IGOILLO-ESTEVE, Mariana ; MARSELLI, Lorella ; MARCHETTI, Piero ; HARDING, Heather P ; RON, David ; EIZIRIK, Décio L ; CNOP, Miriam ; GURZOV, Esteban N ; GERMANO, Carla M ; NAAMANE, Najib ; MARHFOUR, Ihsane ; FUKAYA, Makiko ; VANDERWINDEN, Jean-Marie ; GYSEMANS, Conny ; MATHIEU, Chantal
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2763-2775
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Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species
Author / Creator:Pilkington, Emily H. ; Gurzov, Esteban N. ; Kakinen, Aleksandr ; Litwak, Sara A. ; Stanley, William J. ; Davis, Thomas P. ; Ke, Pu Chun
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-02, Vol.6 (1), p.21274-21274, Article 21274
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Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice
Author / Creator:Brahma, Manoja K ; Xiao, Peng ; Popa, Madalina ; Negueruela, Javier ; Vandenbempt, Valerie ; Demine, Stéphane ; Cardozo, Alessandra K ; Gurzov, Esteban N
Publisher:Basel: MDPI AG
Journal title:Nutrients, 2022-09, Vol.14 (18), p.3866
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Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Author / Creator:Wali, Jibran A ; Galic, Sandra ; Tan, Christina YR ; Gurzov, Esteban N ; Frazier, Ann E ; Connor, Timothy ; Ge, Jingjing ; Pappas, Evan G ; Stroud, David ; Varanasi, L Chitra ; Selck, Claudia ; Ryan, Michael T ; Thorburn, David R ; Kemp, Bruce E ; Krishnamurthy, Balasubramanian ; Kay, Thomas WH ; McGee, Sean L ; Thomas, Helen E
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2018-01, Vol.25 (1), p.217-225
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Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line
Author / Creator:Gurzov, Esteban N ; Nabha, Sanaa M ; Yamamoto, Hamilto ; Meng, Hong ; Scharovsky, O Graciela ; Bonfil, R Daniel
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2007-10, Vol.7 (1), p.184-184, Article 184
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p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity
Author / Creator:Litwak, Sara A. ; Loh, Kim ; Stanley, William J. ; Pappas, Evan G. ; Wali, Jibran A. ; Selck, Claudia ; Strasser, Andreas ; Thomas, Helen E. ; Gurzov, Esteban N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-04, Vol.6 (1), p.23802-23802, Article 23802
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Can GABA turn pancreatic [alpha]-cells into [beta]-cells?
Author / Creator:Eizirik, Decio L ; Gurzov, Esteban N
Publisher:Nature Publishing Group
Journal title:Nature reviews. Endocrinology, 2018-11, Vol.14 (11), p.629
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Showing 1 to 20 of 29 results

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Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges

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Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation

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Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

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SCFA biotherapy delays diabetes in humanized gnotobiotic mice by remodeling mucosal homeostasis and metabolome

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Inhibition of Y1 receptor signaling improves islet transplant outcome

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The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells

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Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance

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Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets

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JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

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Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System

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PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

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Can GABA turn pancreatic α-cells into β-cells?

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Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

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Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress―Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis

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Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species

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Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

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Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice

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Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line

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p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity

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Can GABA turn pancreatic [alpha]-cells into [beta]-cells?

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