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A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors

A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21248112

A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors

About this item

Full title

A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Cancer chemotherapy and pharmacology, 2008-09, Vol.62 (4), p.727-733

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Introduction
Chemotherapy regimens including gemcitabine in combination with microtubule inhibitors such as docetaxel and paclitaxel have wide clinical application. Patupilone is a novel tubulin-polymerizing agent with activity against paclitaxel-resistant cell lines. We conducted a phase I trial to assess the maximum tolerated dose, dose limiti...

Alternative Titles

Full title

A phase I trial of gemcitabine in combination with patupilone in patients with advanced solid tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_21248112

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21248112

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-007-0656-8

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