Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Growing evidence gathered from transgenic animal models of Alzheimer’s disease (AD) indicates that the intraneuronal accumulation of amyloid-β (Aβ) peptides is an early event in the AD pathogenesis, producing cognitive deficits before the deposition of insoluble plaques. Levels of soluble Aβ are also a strong indicator of synaptic deficits and conc...
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Full title
Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex
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TN_cdi_proquest_miscellaneous_2126901137
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2126901137
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ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-018-1922-z