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Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex

Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2126901137

Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex

About this item

Full title

Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2018-12, Vol.136 (6), p.901-917

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Growing evidence gathered from transgenic animal models of Alzheimer’s disease (AD) indicates that the intraneuronal accumulation of amyloid-β (Aβ) peptides is an early event in the AD pathogenesis, producing cognitive deficits before the deposition of insoluble plaques. Levels of soluble Aβ are also a strong indicator of synaptic deficits and conc...

Alternative Titles

Full title

Evidence of intraneuronal Aβ accumulation preceding tau pathology in the entorhinal cortex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2126901137

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2126901137

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-018-1922-z

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