B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of si...
B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Immunoglobulin diversification is absolutely dependent on the action of activation-induced cytidine deaminase, which must be tightly controlled. Honjo and colleagues systematically analyze the regulatory elements that govern expression of the gene encoding this deaminase.
Activation-induced cytidine deaminase (AID) is essential for the generatio...
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B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
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TN_cdi_proquest_miscellaneous_21329733
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21329733
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.1829
