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Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell d...

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21333909

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

About this item

Full title

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2010-02, Vol.11 (2), p.171-179

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

B cell development requires interleukin 7 signals that activate the transcription factor STAT5. Busslinger and colleagues report that STAT5 has a permissive rather than instructive role in pro-B cell survival and immunoglobulin recombination.
STAT5 and interleukin 7 (IL-7) signaling are thought to control B lymphopoiesis by regulating the expres...

Alternative Titles

Full title

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_21333909

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_21333909

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.1827

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