Long-term oncologic after robotic versus laparoscopic right colectomy: a prospective randomized stud...
Long-term oncologic after robotic versus laparoscopic right colectomy: a prospective randomized study
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New York: Springer US
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English
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New York: Springer US
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Objective
The aim of this study was to compare the long-term outcomes of robot-assisted right colectomy (RAC) with those for conventional laparoscopy-assisted right surgery (LAC) for treating right-sided colon cancer.
Background
The enthusiasm for the robotic techniques has gained increasing interest in colorectal malignancies. However, the role of robotic surgery in the oncologic safety has not yet been defined.
Methods
From September 2009 to July 2011, 71 patients with right-sided colonic cancer were randomized in the study. Adjuvant therapy and postoperative follow-up were similar in both groups. The primary and secondary endpoints of the study were hospital stay and survival, respectively. Data were analyzed by intention-to-treat principle.
Results
The RAC and LAC groups did not differ significantly in terms of baseline clinical characteristics. Compared with the LAC group, RAC was associated with longer operation times (195 min vs. 129 min,
P
< 0.001) and higher cost ($12,235 vs. $10,319,
P
= 0.013). The median follow-up was 49.23 months (interquartile range 40.63–56.20). The combined 5-year disease-free rate for all tumor stages was 77.4% (95% confidence interval [CI], 60.6–92.1%) in the RAC group and 83.6% (95% CI 72.1–0.97.0%) in the LAC group (
P
= 0.442). The combined 5-year overall survival rates for all stages were 91.1% (95% CI 78.8–100%) in the RAC group and 91.0% (95% CI 81.3–100%) in the LAC group (
P
= 0.678). Using multivariate analysis, RAC was not a predictor of recurrence.
Conclusions
RAC appears to similar long-term survival as compared with LAC. However, we did not observe any clinical benefits of RAC which could translate to a decrease in expenditures.
Trial registry:
http://www.ClinicalTrials.gov
, number NCT00470951.
Graphical abstract...
Alternative Titles
Full title
Long-term oncologic after robotic versus laparoscopic right colectomy: a prospective randomized study
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2136057214
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2136057214
Other Identifiers
ISSN
0930-2794
E-ISSN
1432-2218
DOI
10.1007/s00464-018-6563-8