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Cytokinesis defects and cancer

Cytokinesis defects and cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2155148842

Cytokinesis defects and cancer

About this item

Full title

Cytokinesis defects and cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2019-01, Vol.19 (1), p.32-45

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Whole-genome and centrosome duplication as a consequence of cytokinesis failure can drive tumorigenesis in experimental model systems. However, whether cytokinesis failure is in fact an important cause of human cancers has remained unclear. In this Review, we summarize evidence that whole-genome-doubling events are frequently observed in human canc...

Alternative Titles

Full title

Cytokinesis defects and cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2155148842

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2155148842

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/s41568-018-0084-6

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