Cytokinesis defects and cancer
Cytokinesis defects and cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Whole-genome and centrosome duplication as a consequence of cytokinesis failure can drive tumorigenesis in experimental model systems. However, whether cytokinesis failure is in fact an important cause of human cancers has remained unclear. In this Review, we summarize evidence that whole-genome-doubling events are frequently observed in human canc...
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Full title
Cytokinesis defects and cancer
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TN_cdi_proquest_miscellaneous_2155148842
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2155148842
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/s41568-018-0084-6