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Pathological priming causes developmental gene network heterochronicity in autistic subject-derived...

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2165060198

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

About this item

Full title

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2019-02, Vol.22 (2), p.243-255

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To profile early neurodevelopmental alterations in ASD with macrocephaly, we monitored subject-derived induced pluripotent stem cells (iPSCs) thro...

Alternative Titles

Full title

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2165060198

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2165060198

Other Identifiers

ISSN

1097-6256,1546-1726

E-ISSN

1546-1726

DOI

10.1038/s41593-018-0295-x

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