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Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of pre...

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of pre...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179349368

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

About this item

Full title

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

Publisher

London: Nature Publishing Group UK

Journal title

Nature nanotechnology, 2019-03, Vol.14 (3), p.260-268

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Deposition of complement factors (opsonization) on nanoparticles may promote clearance from the blood by macrophages and trigger proinflammatory responses, but the mechanisms regulating the efficiency of complement activation are poorly understood. We previously demonstrated that opsonization of superparamagnetic iron oxide (SPIO) nanoworms with th...

Alternative Titles

Full title

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179349368

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179349368

Other Identifiers

ISSN

1748-3387

E-ISSN

1748-3395

DOI

10.1038/s41565-018-0344-3

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