Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of pre...
Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Deposition of complement factors (opsonization) on nanoparticles may promote clearance from the blood by macrophages and trigger proinflammatory responses, but the mechanisms regulating the efficiency of complement activation are poorly understood. We previously demonstrated that opsonization of superparamagnetic iron oxide (SPIO) nanoworms with th...
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Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles
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TN_cdi_proquest_miscellaneous_2179349368
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179349368
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-018-0344-3