Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Many drugs target the serotonin 2A receptor (5-HT
2A
R), including second-generation antipsychotics that also target the dopamine D
2
receptor (D
2
R). These drugs often produce severe side effects due to non-selective binding to other aminergic receptors. Here, we report the structures of human 5-HT
2A
R in complex with the...
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Full title
Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
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TN_cdi_proquest_miscellaneous_2229080198
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2229080198
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-018-0180-z
