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Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neurops...

Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neurops...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231848932

Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms

About this item

Full title

Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2021-03, Vol.26 (3), p.897-906

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The locus coeruleus (LC) supplies norepinephrine to the brain, is one of the first sites of tau deposition in Alzheimer’s disease (AD) and modulates a variety of behaviors and cognitive functions. Transgenic mouse models showed that norepinephrine dysregulation after LC lesions exacerbates inflammatory responses, blood–brain barrier leakage (BBB),...

Alternative Titles

Full title

Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2231848932

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231848932

Other Identifiers

ISSN

1359-4184

E-ISSN

1476-5578

DOI

10.1038/s41380-019-0437-x

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