Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neurops...
Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The locus coeruleus (LC) supplies norepinephrine to the brain, is one of the first sites of tau deposition in Alzheimer’s disease (AD) and modulates a variety of behaviors and cognitive functions. Transgenic mouse models showed that norepinephrine dysregulation after LC lesions exacerbates inflammatory responses, blood–brain barrier leakage (BBB),...
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Alzheimer’s disease pathology: pathways between central norepinephrine activity, memory, and neuropsychiatric symptoms
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TN_cdi_proquest_miscellaneous_2231848932
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231848932
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1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-019-0437-x