Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid linea...
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage
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Dress, Regine J. , Dutertre, Charles-Antoine , Giladi, Amir , Schlitzer, Andreas , Low, Ivy , Shadan, Nurhidaya Binte , Tay, Alicia , Lum, Josephine , Kairi, Muhammad Faris Bin Mohd , Hwang, You Yi , Becht, Etienne , Cheng, Yang , Chevrier, Marion , Larbi, Anis , Newell, Evan W. , Amit, Ido , Chen, Jinmiao and Ginhoux, Florent
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry, in vivo fate mapping and in vitro clonal assays, here we show that, at the single-cell level, the priming of mouse hematopoietic progenitor cells toward the pDC lineage o...
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Full title
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage
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TN_cdi_proquest_miscellaneous_2243484837
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2243484837
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0420-3