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Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid linea...

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid linea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2243484837

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

About this item

Full title

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2019-07, Vol.20 (7), p.852-864

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry, in vivo fate mapping and in vitro clonal assays, here we show that, at the single-cell level, the priming of mouse hematopoietic progenitor cells toward the pDC lineage o...

Alternative Titles

Full title

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2243484837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2243484837

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-019-0420-3

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