R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach
R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Wnt signalling stimulated by binding of R-spondin (Rspo) to Lgr-family members is crucial for gastrointestinal stem cell renewal. Infection of the stomach with
Helicobacter pylori
stimulates increased secretion of Rspo by myofibroblasts, leading to an increase in proliferation of Wnt-responsive Axin2
+
Lgr5
−
stem cells in the ist...
Alternative Titles
Full title
R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach
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Record Identifier
TN_cdi_proquest_miscellaneous_2246906427
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2246906427
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-019-0339-9
