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Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2246912093

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

About this item

Full title

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-06, Vol.570 (7762), p.538-542

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Ribosome-associated quality control (RQC) provides a rescue pathway for eukaryotic cells to process faulty proteins after translational stalling of cytoplasmic ribosomes
1

6
. After dissociation of ribosomes, the stalled tRNA-bound peptide remains associated with the 60S subunit and extended by Rqc2 by addition of C-terminal alanyl an...

Alternative Titles

Full title

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2246912093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2246912093

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1307-z

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