Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis
Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Ribosome-associated quality control (RQC) provides a rescue pathway for eukaryotic cells to process faulty proteins after translational stalling of cytoplasmic ribosomes
1
–
6
. After dissociation of ribosomes, the stalled tRNA-bound peptide remains associated with the 60S subunit and extended by Rqc2 by addition of C-terminal alanyl an...
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Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis
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TN_cdi_proquest_miscellaneous_2246912093
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2246912093
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1307-z