C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia
About this item
Full title
Author / Creator
Savarirayan, Ravi , Irving, Melita , Bacino, Carlos A , Bostwick, Bret , Charrow, Joel , Cormier-Daire, Valerie , Le Quan Sang, Kim-Hanh , Dickson, Patricia , Harmatz, Paul , Phillips, John , Owen, Natalie , Cherukuri, Anu , Jayaram, Kala , Jeha, George S , Larimore, Kevin , Chan, Ming-Liang , Huntsman Labed, Alice , Day, Jonathan and Hoover-Fong, Julie
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Vosoritide is a biologic analogue of C-type natriuretic peptide, a stimulator of endochondral ossification, which is disordered in achondroplasia. In this phase 2 dose-finding study and extension study involving children with achondroplasia, once-daily administration of vosoritide resulted in a sustained increase in the annualized growth velocity.
Alternative Titles
Full title
C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia
Authors, Artists and Contributors
Author / Creator
Irving, Melita
Bacino, Carlos A
Bostwick, Bret
Charrow, Joel
Cormier-Daire, Valerie
Le Quan Sang, Kim-Hanh
Dickson, Patricia
Harmatz, Paul
Phillips, John
Owen, Natalie
Cherukuri, Anu
Jayaram, Kala
Jeha, George S
Larimore, Kevin
Chan, Ming-Liang
Huntsman Labed, Alice
Day, Jonathan
Hoover-Fong, Julie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2252255697
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2252255697
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1813446
