Bromodomains: a new target class for drug development
Bromodomains: a new target class for drug development
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Less than a decade ago, it was shown that bromodomains, acetyl lysine ‘reader’ modules found in proteins with varied functions, were highly tractable small-molecule targets. This is an unusual property for protein–protein or protein–peptide interaction domains, and it prompted a wave of chemical probe discovery to understand the biological potentia...
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Bromodomains: a new target class for drug development
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TN_cdi_proquest_miscellaneous_2253271734
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2253271734
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-019-0030-7
