Calycosin induces apoptosis in adenocarcinoma HT29 cells by inducing cytotoxic autophagy mediated by...
Calycosin induces apoptosis in adenocarcinoma HT29 cells by inducing cytotoxic autophagy mediated by SIRT1/AMPK‐induced inhibition of Akt/mTOR
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Publisher
Australia: Wiley Subscription Services, Inc
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Language
English
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Publisher
Australia: Wiley Subscription Services, Inc
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Contents
Autophagy promotes cell survival or induces apoptosis in cancer cells. While SIRT1 and AMPK induce autophagy in both normal and cancer cells, Akt and mTOR can inhibit it. Calycosin, a methoxyisoflavone, protects against several types of solid tumours including colorectal cancer. However, the mechanisms behind the antitumour effect of Calycosin rema...
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Full title
Calycosin induces apoptosis in adenocarcinoma HT29 cells by inducing cytotoxic autophagy mediated by SIRT1/AMPK‐induced inhibition of Akt/mTOR
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TN_cdi_proquest_miscellaneous_2253299566
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2253299566
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ISSN
0305-1870
E-ISSN
1440-1681
DOI
10.1111/1440-1681.13133
