Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesi...
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis
About this item
Full title
Author / Creator
Esteve, Pilar , Rueda-Carrasco, Javier , Inés Mateo, María , Martin-Bermejo, María Jesús , Draffin, Jonathan , Pereyra, Guadalupe , Sandonís, África , Crespo, Inmaculada , Moreno, Inmaculada , Aso, Ester , Garcia-Esparcia, Paula , Gomez-Tortosa, Estrella , Rábano, Alberto , Fortea, Juan , Alcolea, Daniel , Lleo, Alberto , Heneka, Michael T. , Valpuesta, José M. , Esteban, José A. , Ferrer, Isidro , Domínguez, Mercedes and Bovolenta, Paola
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
The deposition of aggregated amyloid-β peptides derived from the pro-amyloidogenic processing of the amyloid precurson protein (APP) into characteristic amyloid plaques (APs) is distinctive to Alzheimer’s disease (AD). Alternative APP processing via the metalloprotease ADAM10 prevents amyloid-β formation. We tested whether downregulation of ADAM10...
Alternative Titles
Full title
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis
Authors, Artists and Contributors
Author / Creator
Rueda-Carrasco, Javier
Inés Mateo, María
Martin-Bermejo, María Jesús
Draffin, Jonathan
Pereyra, Guadalupe
Sandonís, África
Crespo, Inmaculada
Moreno, Inmaculada
Aso, Ester
Garcia-Esparcia, Paula
Gomez-Tortosa, Estrella
Rábano, Alberto
Fortea, Juan
Alcolea, Daniel
Lleo, Alberto
Heneka, Michael T.
Valpuesta, José M.
Esteban, José A.
Ferrer, Isidro
Domínguez, Mercedes
Bovolenta, Paola
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2258742367
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2258742367
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-019-0432-1
