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5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2267022886

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

About this item

Full title

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2019-08, Vol.21 (8), p.978-990

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although 5-methylcytosine (m
5
C) is a widespread modification in RNAs, its regulation and biological role in pathological conditions (such as cancer) remain unknown. Here, we provide the single-nucleotide resolution landscape of messenger RNA m
5
C modifications in human urothelial carcinoma of the bladder (UCB). We identify numerous o...

Alternative Titles

Full title

5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2267022886

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2267022886

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-019-0361-y

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