5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
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Chen, Xin , Li, Ang , Sun, Bao-Fa , Yang, Ying , Han, Ya-Nan , Yuan, Xun , Chen, Ri-Xin , Wei, Wen-Su , Liu, Yanchao , Gao, Chun-Chun , Chen, Yu-Sheng , Zhang, Mengmeng , Ma, Xiao-Dan , Liu, Zhuo-Wei , Luo, Jun-Hang , Lyu, Cong , Wang, Hai-Lin , Ma, Jinbiao , Zhao, Yong-Liang , Zhou, Fang-Jian , Huang, Ying , Xie, Dan and Yang, Yun-Gui
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Although 5-methylcytosine (m
5
C) is a widespread modification in RNAs, its regulation and biological role in pathological conditions (such as cancer) remain unknown. Here, we provide the single-nucleotide resolution landscape of messenger RNA m
5
C modifications in human urothelial carcinoma of the bladder (UCB). We identify numerous o...
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5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
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TN_cdi_proquest_miscellaneous_2267022886
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2267022886
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-019-0361-y