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Molecular genetic framework underlying pulmonary arterial hypertension

Molecular genetic framework underlying pulmonary arterial hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2272737931

Molecular genetic framework underlying pulmonary arterial hypertension

About this item

Full title

Molecular genetic framework underlying pulmonary arterial hypertension

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews cardiology, 2020-02, Vol.17 (2), p.85-95

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of pulmonary artery smooth muscle cells and fibroblasts. Vascular occlusion can lead to increased pressure in the pulmonary arteries, often resulting in right ventric...

Alternative Titles

Full title

Molecular genetic framework underlying pulmonary arterial hypertension

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2272737931

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2272737931

Other Identifiers

ISSN

1759-5002

E-ISSN

1759-5010

DOI

10.1038/s41569-019-0242-x

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