BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a...
BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
BRCA-1 is a nuclear protein involved in DNA repair, transcriptional regulation, and cell cycle control. Its involvement in other cellular processes has been described. Here, we aimed to investigate the role of BRCA-1 in macrophages M(LPS), M(IL-4), and tumor cell-induced differentiation. We used siRNAs to knockdown BRCA-1 in RAW 264.7 macrophages e...
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Full title
BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism
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TN_cdi_proquest_miscellaneous_2280541486
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2280541486
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ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-019-03605-9
