FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Optical dimerizers have been developed to untangle signaling pathways, but they are of limited use in vivo, partly due to their inefficient activation under two-photon (2P) excitation. To overcome this problem, we developed Förster resonance energy transfer (FRET)-assisted photoactivation, or FRAPA. On 2P excitation, mTagBFP2 efficiently absorbs an...
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FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics
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TN_cdi_proquest_miscellaneous_2288004503
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2288004503
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-019-0541-5
