Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier...
Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier and immune defense defects
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Reactive oxygen species (ROS) generated by NADPH oxidases (NOX/DUOX) provide antimicrobial defense, redox signaling, and gut barrier maintenance. Inactivating NOX variants are associated with comorbid intestinal inflammation in chronic granulomatous disease (CGD; NOX2) and pediatric inflammatory bowel disease (IBD; NOX1); however Nox-deficient mice...
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Full title
Colitis susceptibility in mice with reactive oxygen species deficiency is mediated by mucus barrier and immune defense defects
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TN_cdi_proquest_miscellaneous_2298143901
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2298143901
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ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/s41385-019-0205-x
