Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-st...
Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial
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Author / Creator
Paz-Ares, Luis , Dvorkin, Mikhail , Chen, Yuanbin , Reinmuth, Niels , Hotta, Katsuyuki , Hochmair, Maximilian J , Özgüroğlu, Mustafa , Ji, Jun Ho , Bondarenko, Igor , Byrne, Natalie , Shire, Norah , Goldman, Jonathan W , Batagelj, Emilio , Casarini, Ignacio , Pastor, Anea Viviana , Hartl, Sylvia , Hochmair, Maximilian J , Lamprecht, Bernd , Dos Reis, Peo , Serodio da Rocha Baldotto, Clarissa , Venkova, Violetka , Bi, Minghong , Chen, Zhendong , Han, Zhigang , Hu, Yi , Li, Wei , Ma, Shenglin , Nan, Kejun , Shu, Yongqian , Wang, Kai , Yang, Nong , Zhang, Wei , Zhao, Jun , Zhao, Yanqiu , Zhou, Caicun , Zhou, Xiangdong , Skrickova, Jana , Hilgers, Werner , Moro-Sibilot, Denis , Bischoff, Helge , Lang, Susanne , Fülöp, Anea , Horváth, Zsolt , Laczó, Ibolya , Losonczy, György , Pápai Székely, Zsolt , Telekes, Anás , Bar, Jair , Gottfried, Maya , Heching, Norman Isaac , Bettini, Anna Cecilia , Minelli, Mauro , Roila, Fausto , Verderame, Francesco , Atagi, Shinji , Goto, Hisatsugu , Goto, Koichi , Hara, Yu , Hida, Toyoaki , Hotta, Katsuyuki , Kuyama, Shoichi , Morise, Masahiro , Nakahara, Yasuharu , Okamoto, Isamu , Shinoda, Masahiro , Umemura, Shigeki , Heniks, Lizza , Ungureanu, Anei , Luft, Alexander , Sakaeva, Dina , Smolin, Alexey , Statsenko, Galina , Vasilyev, Alexander , Vladimirova, Lyubov , Chovanec, Jozef , Urda, Michal , Ji, Jun Ho , Lee, Kyung Hee , Isla Casado, Dolores , Ponce Aix, Santiago , Hsia, Te-Chun , Wu, Shang-Yin , Çiçin, Irfan , Göksel, Tuncay , Özgüroğlu, Mustafa , Adamchuk, Hryhoriy , Bondarenko, Igor , Kryzhanivska, Anna , Shevnia, Serhii , Trukhin, Dmytro , Ursol, Grygorii , Voitko, Oleksandr , Vynnychenko, Ihor , Chen, Yuanbin , Chua, Winston , Dakhil, Shaker , Goldman, Jonathan W , Lakhanpal, Shailena , Powell, Steven , Stilwill, Joseph and CASPIAN investigators
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Most patients with small-cell lung cancer (SCLC) have extensive-stage disease at presentation, and prognosis remains poor. Recently, immunotherapy has demonstrated clinical activity in extensive-stage SCLC (ES-SCLC). The CASPIAN trial assessed durvalumab, with or without tremelimumab, in combination with etoposide plus either cisplatin or carboplat...
Alternative Titles
Full title
Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Dvorkin, Mikhail
Chen, Yuanbin
Reinmuth, Niels
Hotta, Katsuyuki
Hochmair, Maximilian J
Özgüroğlu, Mustafa
Ji, Jun Ho
Bondarenko, Igor
Byrne, Natalie
Shire, Norah
Goldman, Jonathan W
Batagelj, Emilio
Casarini, Ignacio
Pastor, Anea Viviana
Hartl, Sylvia
Hochmair, Maximilian J
Lamprecht, Bernd
Dos Reis, Peo
Serodio da Rocha Baldotto, Clarissa
Venkova, Violetka
Bi, Minghong
Chen, Zhendong
Han, Zhigang
Hu, Yi
Li, Wei
Ma, Shenglin
Nan, Kejun
Shu, Yongqian
Wang, Kai
Yang, Nong
Zhang, Wei
Zhao, Jun
Zhao, Yanqiu
Zhou, Caicun
Zhou, Xiangdong
Skrickova, Jana
Hilgers, Werner
Moro-Sibilot, Denis
Bischoff, Helge
Lang, Susanne
Fülöp, Anea
Horváth, Zsolt
Laczó, Ibolya
Losonczy, György
Pápai Székely, Zsolt
Telekes, Anás
Bar, Jair
Gottfried, Maya
Heching, Norman Isaac
Bettini, Anna Cecilia
Minelli, Mauro
Roila, Fausto
Verderame, Francesco
Atagi, Shinji
Goto, Hisatsugu
Goto, Koichi
Hara, Yu
Hida, Toyoaki
Hotta, Katsuyuki
Kuyama, Shoichi
Morise, Masahiro
Nakahara, Yasuharu
Okamoto, Isamu
Shinoda, Masahiro
Umemura, Shigeki
Heniks, Lizza
Ungureanu, Anei
Luft, Alexander
Sakaeva, Dina
Smolin, Alexey
Statsenko, Galina
Vasilyev, Alexander
Vladimirova, Lyubov
Chovanec, Jozef
Urda, Michal
Ji, Jun Ho
Lee, Kyung Hee
Isla Casado, Dolores
Ponce Aix, Santiago
Hsia, Te-Chun
Wu, Shang-Yin
Çiçin, Irfan
Göksel, Tuncay
Özgüroğlu, Mustafa
Adamchuk, Hryhoriy
Bondarenko, Igor
Kryzhanivska, Anna
Shevnia, Serhii
Trukhin, Dmytro
Ursol, Grygorii
Voitko, Oleksandr
Vynnychenko, Ihor
Chen, Yuanbin
Chua, Winston
Dakhil, Shaker
Goldman, Jonathan W
Lakhanpal, Shailena
Powell, Steven
Stilwill, Joseph
CASPIAN investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2302479613
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2302479613
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(19)32222-6
