The great escape: tumour cell plasticity in resistance to targeted therapy
The great escape: tumour cell plasticity in resistance to targeted therapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The success of targeted therapies in cancer treatment has been impeded by various mechanisms of resistance. Besides the acquisition of resistance-conferring genetic mutations, reversible mechanisms that lead to drug tolerance have emerged. Plasticity in tumour cells drives their transformation towards a phenotypic state that no longer depends on th...
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Full title
The great escape: tumour cell plasticity in resistance to targeted therapy
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TN_cdi_proquest_miscellaneous_2305042005
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2305042005
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-019-0044-1
