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A resource-efficient tool for mixed model association analysis of large-scale data

A resource-efficient tool for mixed model association analysis of large-scale data

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2318733184

A resource-efficient tool for mixed model association analysis of large-scale data

About this item

Full title

A resource-efficient tool for mixed model association analysis of large-scale data

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2019-12, Vol.51 (12), p.1749-1755

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The genome-wide association study (GWAS) has been widely used as an experimental design to detect associations between genetic variants and a phenotype. Two major confounding factors, population stratification and relatedness, could potentially lead to inflated GWAS test statistics and hence to spurious associations. Mixed linear model (MLM)-based...

Alternative Titles

Full title

A resource-efficient tool for mixed model association analysis of large-scale data

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2318733184

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2318733184

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-019-0530-8

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