USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback...
USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation
About this item
Full title
Author / Creator
Ling, Sunbin , Shan, Qiaonan , Zhan, Qifan , Ye, Qianwei , Liu, Peng , Xu, Shengjun , He, Xin , Ma, Jian , Xiang, Jiajia , Jiang, Guangjiang , Wen, Xue , Feng, Zijie , Wu, Yuan , Feng, Tingting , Xu, Li , Chen, Kangchen , Zhang, Xuanyu , Wei, Rongli , Zhang, Chenzhi , Cen, Beini , Xie, Haiyang , Song, Penghong , Liu, Jimin , Zheng, Shusen and Xu, Xiao
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveWe aimed to elucidate the mutual regulation mechanism of ubiquitin-specific protease 22 (USP22) and hypoxia inducible factor-1α (HIF1α), and the mechanism they promote the stemness of hepatocellular carcinoma (HCC) cells under hypoxic conditions.DesignCell counting, migration, self-renewal ability, chemoresistance and expression of stemnes...
Alternative Titles
Full title
USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation
Authors, Artists and Contributors
Author / Creator
Shan, Qiaonan
Zhan, Qifan
Ye, Qianwei
Liu, Peng
Xu, Shengjun
He, Xin
Ma, Jian
Xiang, Jiajia
Jiang, Guangjiang
Wen, Xue
Feng, Zijie
Wu, Yuan
Feng, Tingting
Xu, Li
Chen, Kangchen
Zhang, Xuanyu
Wei, Rongli
Zhang, Chenzhi
Cen, Beini
Xie, Haiyang
Song, Penghong
Liu, Jimin
Zheng, Shusen
Xu, Xiao
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2319487864
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2319487864
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2019-319616
