The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer
The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer
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Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
TOPARP-B was a randomised, phase 2 study that compared 300 mg versus 400 mg twice daily oral olaparib through a pick-the-winner design. 711 patients previously treated with chemotherapy consented to prescreening, of whom 592 underwent targeted next-generation sequencing for DDR aberrations. [...]119 (17%) patients in TOPARP-B could not be molecular...
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Full title
The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer
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TN_cdi_proquest_miscellaneous_2322740678
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2322740678
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ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(19)30780-6