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The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer

The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2322740678

The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer

About this item

Full title

The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2020-01, Vol.21 (1), p.17-19

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

TOPARP-B was a randomised, phase 2 study that compared 300 mg versus 400 mg twice daily oral olaparib through a pick-the-winner design. 711 patients previously treated with chemotherapy consented to prescreening, of whom 592 underwent targeted next-generation sequencing for DDR aberrations. [...]119 (17%) patients in TOPARP-B could not be molecular...

Alternative Titles

Full title

The tip of the iceberg: predicting PARP inhibitor efficacy in prostate cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2322740678

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2322740678

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(19)30780-6

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