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Poly (ADP-ribose) Polymerase Inhibition in Patients with Breast Cancer and BRCA 1 and 2 Mutations

Poly (ADP-ribose) Polymerase Inhibition in Patients with Breast Cancer and BRCA 1 and 2 Mutations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2324912406

Poly (ADP-ribose) Polymerase Inhibition in Patients with Breast Cancer and BRCA 1 and 2 Mutations

About this item

Full title

Poly (ADP-ribose) Polymerase Inhibition in Patients with Breast Cancer and BRCA 1 and 2 Mutations

Publisher

Cham: Springer International Publishing

Journal title

Drugs (New York, N.Y.), 2020-02, Vol.80 (2), p.131-146

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

The poly-(ADP-ribose) polymerase (PARP) inhibitors olaparib and talazoparib, have recently been approved for use in patients with metastatic breast cancer (BC) and germline BRCA 1 or 2 mutations due to improved progression-free survival compared to chemotherapy. An increasing number of clinical trials are evaluating the role of PARP inhibitors (PAR...

Alternative Titles

Full title

Poly (ADP-ribose) Polymerase Inhibition in Patients with Breast Cancer and BRCA 1 and 2 Mutations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2324912406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2324912406

Other Identifiers

ISSN

0012-6667

E-ISSN

1179-1950

DOI

10.1007/s40265-019-01235-5

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