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Mechanisms of tissue and cell-type specificity in heritable traits and diseases

Mechanisms of tissue and cell-type specificity in heritable traits and diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2334697791

Mechanisms of tissue and cell-type specificity in heritable traits and diseases

About this item

Full title

Mechanisms of tissue and cell-type specificity in heritable traits and diseases

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Genetics, 2020-03, Vol.21 (3), p.137-150

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hundreds of heritable traits and diseases that are caused by germline aberrations in ubiquitously expressed genes manifest in a remarkably limited number of cell types and tissues across the body. Unravelling mechanisms that govern their tissue-specific manifestations is critical for our understanding of disease aetiologies and may direct efforts t...

Alternative Titles

Full title

Mechanisms of tissue and cell-type specificity in heritable traits and diseases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2334697791

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2334697791

Other Identifiers

ISSN

1471-0056

E-ISSN

1471-0064

DOI

10.1038/s41576-019-0200-9

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