Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-r...
Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy
About this item
Full title
Author / Creator
Zhu, Yi , Han, Xi-Qiong , Sun, Xue-Jiao , Yang, Rui , Ma, Wen-Qi and Liu, Nai-Feng
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
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Scope and Contents
Contents
Arterial media calcification is related to mitochondrial dysfunction. Protective mitophagy delays the progression of vascular calcification. We previously reported that lactate accelerates osteoblastic phenotype transition of VSMC through BNIP3-mediated mitophagy suppression. In this study, we investigated the specific links between lactate, mitoch...
Alternative Titles
Full title
Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2348231399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2348231399
Other Identifiers
ISSN
1360-8185
E-ISSN
1573-675X
DOI
10.1007/s10495-020-01592-7
