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Phase separation organizes the site of autophagosome formation

Phase separation organizes the site of autophagosome formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2352052934

Phase separation organizes the site of autophagosome formation

About this item

Full title

Phase separation organizes the site of autophagosome formation

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-02, Vol.578 (7794), p.301-305

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Many biomolecules undergo liquid–liquid phase separation to form liquid-like condensates that mediate diverse cellular functions
1
,
2
. Autophagy is able to degrade such condensates using autophagosomes—double-membrane structures that are synthesized de novo at the pre-autophagosomal structure (PAS) in yeast
3

5
. Whereas...

Alternative Titles

Full title

Phase separation organizes the site of autophagosome formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2352052934

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2352052934

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-1977-6

How to access this item