Immunohistochemical detection of the pro-apoptotic Bax∆2 protein in human tissues
Immunohistochemical detection of the pro-apoptotic Bax∆2 protein in human tissues
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
The pro-apoptotic Bax isoform Bax∆2 was originally discovered in cancer patients with a microsatellite guanine deletion (G8 to G7). This deletion leads to an early stop codon; however, when combined with the alternative splicing of exon 2, the reading frame is restored allowing production of a full-length protein (Bax∆2). Unlike the parental Baxα,...
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Full title
Immunohistochemical detection of the pro-apoptotic Bax∆2 protein in human tissues
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TN_cdi_proquest_miscellaneous_2381847021
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2381847021
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ISSN
0948-6143
E-ISSN
1432-119X
DOI
10.1007/s00418-020-01874-w