Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-...
Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial
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Author / Creator
Trigo, José, MD , Subbiah, Vivek, MD , Besse, Benjamin, Prof , Moreno, Victor, MD , López, Rafael, MD , Sala, María Angeles, MD , Peters, Solange, MD , Ponce, Santiago, MD , Fernández, Cristian, MD , Alfaro, Vicente, PhD , Gómez, Javier, MSc , Kahatt, Carmen, MD , Zeaiter, Ali, MD , Zaman, Khalil, MD , Boni, Valentina, MD , Arrondeau, Jennifer, MD , Martínez, Maite, MD , Delord, Jean-Pierre, Prof , Awada, Ahmad, MD , Kristeleit, Rebecca, MD , Olmedo, Maria Eugenia, MD , Wannesson, Luciano, MD , Valdivia, Javier, MD , Rubio, María Jesús, MD , Anton, Antonio, MD , Sarantopoulos, John, MD , Chawla, Sant P, MD , Mosquera-Martinez, Joaquín, MD , D'Arcangelo, Manolo, MD , Santoro, Armando, Prof , Villalobos, Victor M, MD , Sands, Jacob, MD and Paz-Ares, Luis, MD
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundFew options exist for treatment of patients with small-cell lung cancer (SCLC) after failure of first-line therapy. Lurbinectedin is a selective inhibitor of oncogenic transcription. In this phase 2 study, we evaluated the acti and safety of lurbinectedin in patients with SCLC after failure of platinum-based chemotherapy. MethodsIn...
Alternative Titles
Full title
Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial
Authors, Artists and Contributors
Author / Creator
Subbiah, Vivek, MD
Besse, Benjamin, Prof
Moreno, Victor, MD
López, Rafael, MD
Sala, María Angeles, MD
Peters, Solange, MD
Ponce, Santiago, MD
Fernández, Cristian, MD
Alfaro, Vicente, PhD
Gómez, Javier, MSc
Kahatt, Carmen, MD
Zeaiter, Ali, MD
Zaman, Khalil, MD
Boni, Valentina, MD
Arrondeau, Jennifer, MD
Martínez, Maite, MD
Delord, Jean-Pierre, Prof
Awada, Ahmad, MD
Kristeleit, Rebecca, MD
Olmedo, Maria Eugenia, MD
Wannesson, Luciano, MD
Valdivia, Javier, MD
Rubio, María Jesús, MD
Anton, Antonio, MD
Sarantopoulos, John, MD
Chawla, Sant P, MD
Mosquera-Martinez, Joaquín, MD
D'Arcangelo, Manolo, MD
Santoro, Armando, Prof
Villalobos, Victor M, MD
Sands, Jacob, MD
Paz-Ares, Luis, MD
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2384844268
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2384844268
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ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(20)30068-1