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A general carbonyl alkylative amination for tertiary amine synthesis

A general carbonyl alkylative amination for tertiary amine synthesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2388000879

A general carbonyl alkylative amination for tertiary amine synthesis

About this item

Full title

A general carbonyl alkylative amination for tertiary amine synthesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-05, Vol.581 (7809), p.415-420

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The ubiquity of tertiary alkylamines in pharmaceutical and agrochemical agents, natural products and small-molecule biological probes
1
,
2
has stimulated efforts towards their streamlined synthesis
3

9
. Arguably the most robust method for the synthesis of tertiary alkylamines is carbonyl reductive amination
3
, whi...

Alternative Titles

Full title

A general carbonyl alkylative amination for tertiary amine synthesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2388000879

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2388000879

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2213-0

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