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Roles and mechanisms of alternative splicing in cancer — implications for care

Roles and mechanisms of alternative splicing in cancer — implications for care

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2391974602

Roles and mechanisms of alternative splicing in cancer — implications for care

About this item

Full title

Roles and mechanisms of alternative splicing in cancer — implications for care

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Clinical oncology, 2020-08, Vol.17 (8), p.457-474

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Removal of introns from messenger RNA precursors (pre-mRNA splicing) is an essential step for the expression of most eukaryotic genes. Alternative splicing enables the regulated generation of multiple mRNA and protein products from a single gene. Cancer cells have general as well as cancer type-specific and subtype-specific alterations in the splic...

Alternative Titles

Full title

Roles and mechanisms of alternative splicing in cancer — implications for care

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2391974602

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2391974602

Other Identifiers

ISSN

1759-4774

E-ISSN

1759-4782

DOI

10.1038/s41571-020-0350-x

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