A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for t...
A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus
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Publisher
New York: Springer US
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Language
English
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New York: Springer US
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Contents
A population pharmacokinetic/pharmacodynamic (popPK/PD) model for BIIB059 (anti-blood dendritic cell antigen 2 [anti-BDCA2]), a humanized immunoglobulin G1 monoclonal antibody currently under development for the treatment of SLE and CLE, is presented. BIIB059 binds BDCA2, a plasmacytoid dendritic cell (pDC)-specific receptor that inhibits the produ...
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Full title
A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus
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TN_cdi_proquest_miscellaneous_2395257978
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2395257978
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ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1007/s10928-020-09688-y