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A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for t...

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2395257978

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus

About this item

Full title

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus

Publisher

New York: Springer US

Journal title

Journal of pharmacokinetics and pharmacodynamics, 2020-06, Vol.47 (3), p.255-266

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

A population pharmacokinetic/pharmacodynamic (popPK/PD) model for BIIB059 (anti-blood dendritic cell antigen 2 [anti-BDCA2]), a humanized immunoglobulin G1 monoclonal antibody currently under development for the treatment of SLE and CLE, is presented. BIIB059 binds BDCA2, a plasmacytoid dendritic cell (pDC)-specific receptor that inhibits the produ...

Alternative Titles

Full title

A clinical population pharmacokinetic/pharmacodynamic model for BIIB059, a monoclonal antibody for the treatment of systemic and cutaneous lupus erythematosus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2395257978

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2395257978

Other Identifiers

ISSN

1567-567X

E-ISSN

1573-8744

DOI

10.1007/s10928-020-09688-y

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