Manganese catalyst enables exploration of the magic methyl effect
Manganese catalyst enables exploration of the magic methyl effect
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The addition of a methyl group to a drug molecule can greatly alter the drug’s pharmacological properties. A catalyst has been developed that enables this ‘magic methyl effect’ to be rapidly explored for drug discovery.
Late-stage functionalization of complex organic molecules.
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Manganese catalyst enables exploration of the magic methyl effect
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TN_cdi_proquest_miscellaneous_2396858530
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2396858530
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/d41586-020-01167-1