BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remo...
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling
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Author / Creator
Yu, Shengyong , Zhou, Chunhua , Cao, Shangtao , He, Jiangping , Cai, Baomei , Wu, Kaixin , Qin, Yue , Huang, Xingnan , Xiao, Lizhan , Ye, Jing , Xu, Shuyang , Xie, Wenxiu , Kuang, Junqi , Chu, Shilong , Guo, Jing , Liu, He , Pang, Wei , Guo, Lin , Zeng, Mengying , Wang, Xiaoshan , Luo, Rongping , Li, Chen , Zhao, Guoqing , Wang, Bo , Wu, Linlin , Chen, Jiekai , Liu, Jing and Pei, Duanqing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
BMP4 regulates a plethora of developmental processes, including the dorsal–ventral axis and neural patterning. Here, we report that BMP4 reconfigures the nuclear architecture during the primed-to-naive transition (PNT). We first established a BMP4-driven PNT and show that BMP4 orchestrates the chromatin accessibility dynamics during PNT. Among the...
Alternative Titles
Full title
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling
Authors, Artists and Contributors
Author / Creator
Zhou, Chunhua
Cao, Shangtao
He, Jiangping
Cai, Baomei
Wu, Kaixin
Qin, Yue
Huang, Xingnan
Xiao, Lizhan
Ye, Jing
Xu, Shuyang
Xie, Wenxiu
Kuang, Junqi
Chu, Shilong
Guo, Jing
Liu, He
Pang, Wei
Guo, Lin
Zeng, Mengying
Wang, Xiaoshan
Luo, Rongping
Li, Chen
Zhao, Guoqing
Wang, Bo
Wu, Linlin
Chen, Jiekai
Liu, Jing
Pei, Duanqing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2401805529
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2401805529
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-020-0516-x
