Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interferi...
Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We previously identified that the development of early-stage myeloid-derived suppressor cells (eMDSCs) in breast cancer with high IL-6 (IL-6
high
) expression was correlated with the SOCS3 deficiency-dependent hyperactivation of the JAK/STAT signaling pathway. However, the regulatory mechanisms have not yet been elucidated. In this study, we...
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Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer
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TN_cdi_proquest_miscellaneous_2402431522
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2402431522
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0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-1322-4
