Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inh...
Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Objectives
Monocarboxylate transporters (MCT) 1, 2 and 4 play an important role in tumor metabolism. The amount of lactate transported by MCT’s highly correlates with overall survival. Furthermore, glycolysis and hypoxia are possible causes for radiation resistance.
Materials and methods
An oral squamous cell carcinoma cell line (CAL27, AT...
Alternative Titles
Full title
Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_2409641983
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2409641983
Other Identifiers
ISSN
1432-6981
E-ISSN
1436-3771
DOI
10.1007/s00784-020-03364-8