A scalable SCENIC workflow for single-cell gene regulatory network analysis
A scalable SCENIC workflow for single-cell gene regulatory network analysis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
This protocol explains how to perform a fast SCENIC analysis alongside standard best practices steps on single-cell RNA-sequencing data using software containers and Nextflow pipelines. SCENIC reconstructs regulons (i.e., transcription factors and their target genes) assesses the activity of these discovered regulons in individual cells and uses th...
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A scalable SCENIC workflow for single-cell gene regulatory network analysis
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TN_cdi_proquest_miscellaneous_2415305313
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2415305313
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-020-0336-2