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A scalable SCENIC workflow for single-cell gene regulatory network analysis

A scalable SCENIC workflow for single-cell gene regulatory network analysis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2415305313

A scalable SCENIC workflow for single-cell gene regulatory network analysis

About this item

Full title

A scalable SCENIC workflow for single-cell gene regulatory network analysis

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2020-07, Vol.15 (7), p.2247-2276

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This protocol explains how to perform a fast SCENIC analysis alongside standard best practices steps on single-cell RNA-sequencing data using software containers and Nextflow pipelines. SCENIC reconstructs regulons (i.e., transcription factors and their target genes) assesses the activity of these discovered regulons in individual cells and uses th...

Alternative Titles

Full title

A scalable SCENIC workflow for single-cell gene regulatory network analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2415305313

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2415305313

Other Identifiers

ISSN

1754-2189

E-ISSN

1750-2799

DOI

10.1038/s41596-020-0336-2

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