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IConMHC: a deep learning convolutional neural network model to predict peptide and MHC-I binding aff...

IConMHC: a deep learning convolutional neural network model to predict peptide and MHC-I binding aff...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2416944770

IConMHC: a deep learning convolutional neural network model to predict peptide and MHC-I binding affinity

About this item

Full title

IConMHC: a deep learning convolutional neural network model to predict peptide and MHC-I binding affinity

Author / Creator

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Immunogenetics (New York), 2020-07, Vol.72 (5), p.295-304

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Tumor-specific neoantigens are mutated self-peptides presented by tumor cell major histocompatibility complex (MHC) molecules and are necessary to elicit host’s anti-cancer cytotoxic T cell responses. It could be specifically recognized by neoantigen-specific T cell receptors (TCRs). However, current wet-lab assays for identifying peptide MHC bindi...

Alternative Titles

Full title

IConMHC: a deep learning convolutional neural network model to predict peptide and MHC-I binding affinity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2416944770

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2416944770

Other Identifiers

ISSN

0093-7711

E-ISSN

1432-1211

DOI

10.1007/s00251-020-01163-9

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