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Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2419084673

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

About this item

Full title

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2020-08, Vol.27 (8), p.726-734

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The HIV-1 envelope glycoprotein (Env) trimer, composed of gp120 and gp41 subunits, mediates viral entry into cells. Recombinant Env trimers have been studied structurally, but characterization of Env embedded in intact virus membranes has been limited to low resolution. Here, we deploy cryo-electron tomography and subtomogram averaging to determine...

Alternative Titles

Full title

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2419084673

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2419084673

Other Identifiers

ISSN

1545-9993,1545-9985

E-ISSN

1545-9985

DOI

10.1038/s41594-020-0452-2

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